Case Report: Role of Low-Carbohydrate, High-Protein (LCHP) Diet in Pre-Operative Weight Loss for Obese Patient with Partially Obstructed Colon Cancer
Abstract
This report describes the case of a 64-year-old female with morbid obesity (BMI 70) diagnosed with a partially obstructing adenocarcinoma of the transverse colon in August 2023 following episode of PR (per rectal) bleeding. The patient's high BMI makes her a significant anaesthetic risk, requiring preoperative weight loss through a low-carbohydrate, highprotein (LCHP) diet. She achieved a remarkable weight loss before undergoing a successful robotic-assisted right hemicolectomy in February 2024. A repeat CT scan performed prior to surgery showed no evidence of metastatic disease despite the delayed treatment. This case emphasises the importance of tailored, multidisciplinary care in managing colorectal cancer in obese patients with comorbidities and highlights the role of dietary interventions in weight management and cancer care.
Keywords
Download Options
Introduction
Colorectal cancer (CRC) is a leading cause of cancer-related morbidity and mortality worldwide (1, 2). Obesity is a known risk factor for CRC (3) and have significant challenges for treatment, including increased surgical and anaesthetic risks (4). Furthermore, dietary patterns play a crucial role in weight management and cancer prevention (5). This report highlights the case of a morbidly obese patient who successfully underwent delayed surgical treatment for partially obstructed transverse colon adenocarcinoma after significant preoperative weight loss through a structured dietary intervention.
Conclusion
LCHP diets must be approached cautiously in CRC patients due to potential negative impacts on gut health and long-term cancer outcomes although, it look promising in altering cancer metabolism and supporting muscle mass preservation.