Pre-Diabetes State: Anthropometric and Haematological Parameters
Abstract
Diabetic is a well known public health problem of today. There are many risk factors of it, which can be identified in pre-diabetic state. So the present study was conducted with the aim to know the status of anthropometric and haematological parameters in pre-diabetic states. For this hospital based study pre-diabetic subjects were identified from first degree relatives of type 2 DM Patients, enrolled in diabetic research centre P.B.M. hospital Bikaner. Relevant investigations were done. Data thus collected on semi-structured questionnaire and analysed using content analysis. Data analysis revealed that although mean Body Mass Index (BMI) was within normal range but Waist circumference (WC), West Hip (W/H) Ratio, Systolic blood pressure were higher than the normal range accepted for that parameter. But mean value of all the studied haematological parameter were within the normal range accepted for that parameter. So it can be conclude that anthropology of an individual may be associated with the pre-diabetic state. Hypertension was found in 25.35% of pre-diabetics. Further researches are necessary to find out this possible association of anthropologic parameter and prediabetic state.
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Introduction
Diabetes mellitus (DM) is a public health problem worldwide causing a substantial increase in morbidity and mortality. The prevalence of type 2 diabetes is increasing worldwide and exhibits a challenge on the health care system as well as on the public health and socioeconomic development of all nations.1
The causes of type 2 diabetes are multifactorial and result from a combination of environmental and genetic risk factors. 2 The implementation of preventive measures in populations and the identification of high risk groups, which mostly benefit from such activities, is the key point for the early prevention of type 2 diabetes and its complications. Since many years, a number of potential risk factors for type 2 diabetes have been identified. In this context, one’s attention was particularly turned on lifestyle risk factors, inflammatory parameters, metabolic abnormalities, and genetic risk factors, many of which have been found to be independently associated with type 2 diabetes. 3
Among those risk factors, routinely measured haematological parameters, such as White Blood Cell (WBC) count and hematocrit (HCT) level were associated with insulin resistance and incident type 2 diabetes. 4-8 Hematocrit is positively correlated with hyperinsulinemia and risk factors associated with insulin resistance, e.g. high blood pressure, elevated serum triglycerides, low HDL cholesterol, and central obesity and could therefore be related to insulin resistance. Furthermore, hematocrit is a major determinant of blood viscosity.
Conclusion
It can be concluded from this present study that although hematological parameters were within normal range but anthropometric parameter were higher in pre-diabetics than the normal range. Prevelance of hypertension was 25.35% in these pre-diabetics in this present study. As there were no comparison group in this study, so to find out the association of various hematological and anthropometric parameters future researches are proposed with appropriate sample size and better study designs.